Episode Details

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱

Thank you to our sponsors:

EVY - https://www.optoceutics.com/perlmutter

and the code perlmutter26 will be auto-applied to your order to get $200 off & free shipping (90 days risk-free).

Fresh Pressed Olive Oil - https://www.getfresh389.com

For a complimentary bottle of one of the greatest olive oils I've ever discovered.

3x4 Genetics - http://3x4genetics.com/DrPerlmutter

for a special offer when you sign up to decode your genetics and get personalized, science-backed health recommendations.

====

Dr. Perlmutter’s groundbreaking new book, Brain Defenders, is now available for pre-order. Discover how to protect your brain and future health - reserve your copy today at https://www.braindefenders.com.

====

00:00 Intro

04:49 Andrew Koutnik’s Story Obesity Type 1 Diabetes and Metabolism

09:44 Ketogenic Diets and Type 1 Diabetes

20:15 Sponsor Break - Optoceutics

21:28 Why This Goes Far Beyond Type 1 Diabetes

26:59 Why Low Carb Diabetes Care Was Abandoned

31:49 Ketosis vs Diabetic Ketoacidosis

35:10 Sponsor Break - Fresh Pressed Olive Oil

37:04 How to Measure Ketone Levels

39:13 Are Breath Ketone Tests Reliable

40:15 What Beta Hydroxybutyrate Actually Does

42:39 Exogenous Ketones and High Altitude Performance

45:49 Sponsor Break - 3X4 Genetics

48:33 MCT Oil and Ketone Production

52:52 The Carb Loading Myth in Sports Performance

1:00:06 Metabolic Flexibility and Keto Adaptation

1:03:17 Rethinking Hypoglycemia in Keto Adapted Athletes

1:07:19 How Carbohydrates Shut Down Fat Burning

1:09:58 Body Fat vs Glycogen as Fuel

1:14:34 What This Means for Endurance Athletes

1:16:17 Fat Metabolism as a Survival Mechanism

1:18:09 The New USDA Dietary Guidelines

1:20:46 Ultra Processed Food and Alzheimer’s Risk

1:22:40 Final Thoughts on Metabolic Flexibility

====

Dr. Andrew Koutnik is a research scientist focused on how nutrition, metabolism, and lifestyle can optimize human health, performance, and resilience. Living with type 1 diabetes for over 17 years, his work bridges personal experience with cutting-edge science across chronic disease and extreme environments.

He earned his PhD in Medical Sciences from the University of South Florida and has led research funded by organizations including NASA, the Department of Defense, and the NIH, contributing to over 100 scientific publications and presentations. His work spans exercise physiology, cardiometabolic health, and therapeutic nutrition.

At Florida State University, Dr. Koutnik studies dietary strategies for diabetes, obesity, and performance under metabolic stress, collaborating with leading institutions worldwide. His mission is to advance evidence-based approaches that empower individuals to improve metabolic health and performance.

___________________________

Instagram: https://www.instagram.com/davidperlmutter/

Website: https://www.drperlmutter.com/

Subscribe to our channel:

https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1