Episode Details

Up+Adam March 16, 2026 Sponsored by Portabidet

What happens when the world decides your story before the truth has a chance to catch up?

In this episode of Up+Adam, Adam sits down with Amanda Knox for a conversation about certainty, conviction, and the stories we tell when we desperately want answers. Knox spent four years in an Italian prison and nearly a decade fighting to clear her name after being wrongfully convicted in a case that captured global headlines. Today she’s an author, journalist, public speaker, and advocate for criminal justice reform who studies how media narratives and public opinion can shape the pursuit of justice.

Her latest project, Doubt: The Case of Lucy Letby, examines one of the most shocking criminal cases in the United Kingdom involving former neonatal nurse Lucy Letby. In the podcast, Knox revisits the evidence and asks a difficult question that many people are afraid to explore: is the case truly as open and shut as the world believes? Drawing from her own experience of wrongful conviction, Knox looks at how institutional pressure, media narratives, and the human desire for simple answers can sometimes overpower complexity.

Adam and Amanda dive into the psychology of certainty, why people instinctively want to pin guilt on someone when tragedy strikes, and how easy it is for investigations and headlines to take on a life of their own. They also talk about something unexpected in Knox’s story: her success in stand-up comedy. For Knox, humor has become a way to reclaim her narrative and process the absurd situations she still finds herself in. As she explains in the conversation, sometimes the choice in dark moments is simple. You can cry about the absurdity of it all, or you can laugh and keep moving forward.

• Listen to the podcast Doubt: The Case of Lucy Letby

https://www.iheart.com/podcast/1119-doubt-the-case-of-lucy-le-321229564/about

• Amanda Knox official website

https://www.amandaknox.com

• Amanda Knox book FREE: My Search for Meaning

https://www.amandaknox.com/writing.html

• Follow Amanda Knox on Instagram

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