Episode Details

A TWiV duo reviews how SARS-CoV-2 attacks the olfactory mucosa but spares the olfactory bulb, vaccination with BNT162b2 induces virus-specific stem cell memory T cells, and development of an oral protease inhibitor for the treatment of COVID-19.

Hosts: Vincent Racaniello and Brianne Barker

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Links for this episode

• How SARS-CoV-2 attacks olfactory mucosa (Cell)
• SARS-CoV-2-specific stem cell memory T cells after mRNA vaccine (Sci Immunol)
• Oral SARS-CoV-2 protease inhibitor (Science)
• Paxlovid phase 2/3 trial preliminary results (Pfizer)
• Letters read on TWiV 829
• Timestamps by Jolene. Thanks!

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Brianne – Coronavirus Neutralizing Antibodies and mRNA Vaccine Video
Vincent – MHC restriction of cytotoxic T cell lysis (Nobel description)

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Intro music is by Ronald Jenkees

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