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In this episode of DX Today, we explore the monumental shift from predictive automation to agentic artificial intelligence within the transportation and logistics sector. While traditional systems have long served as simple records of data or predictive tools for human operators, the emergence of agentic AI introduces software capable of independent reasoning, tool usage, and goal-oriented action. We dive into how these autonomous agents are moving beyond merely flagging delays to actively resolving them by negotiating freight rates, rerouting shipments, and managing complex compliance documentation without constant human oversight. This transition marks a new era where the supply chain evolves into a self-healing system, decoupling business growth from manual labor while addressing the chronic volatility and labor shortages currently facing the global market.We also take a deep dive into the technical architectures and real-world case studies currently defining the landscape, from Uber Freights digital brokerage innovations to Blue Yonders advanced supply chain orchestrators. The discussion covers the critical hurdles facing widespread adoption, including the emerging legal liability gap for autonomous errors and the technical challenges of integrating sophisticated AI with legacy enterprise systems. Looking toward 2030, we examine the future of agent-to-agent commerce and the changing role of logistics professionals as they transition into governance officers for vast fleets of digital agents. This episode provides essential strategic recommendations for leaders looking to navigate the risks and rewards of this technological frontier to build more resilient and efficient global trade networks.