Episode Details

Have you ever heard of inositol? Could you be deficient and not even realize it? If you’re struggling with blood sugar swings, irregular cycles, anxiety, or 2am wake-ups, could this overlooked compound be a missing piece? While magnesium, B vitamins, and electrolytes dominate most wellness conversations, myo-inositol plays a critical role in insulin signaling, ovarian function, and neurotransmitter balance, acting as an intracellular messenger that helps your cells properly respond to hormonal cues.

This episode unpacks what myo-inositol actually is, how it functions in the body, and what the research shows in areas like PCOS, insulin resistance, fertility, mood disorders, and sleep. It also covers therapeutic dosing, food sources, and how to use supplementation strategically for clinical outcomes. Whether you’re navigating hormone imbalance, metabolic dysfunction, or nervous system dysregulation, this conversation takes a deeper look at why myo-inositol deserves far more attention in root-cause medicine.

Also in this episode:

• • What is inositol?
  • What does it do in the body?
  • What causes myoinositol deficiency?
  • Symptoms of deficiency
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  • Inositol and Metabolic Health
    • Ovulatory and Metabolic Effects of d-Chiro-Inositol in the Polycystic Ovary Syndrome | New England Journal of Medicine
    • Effects of inositol on ovarian function and metabolic factors in women with PCOS: a randomized double blind placebo-controlled trial - PubMed
    • Potential role and therapeutic interests of myo-inositol in metabolic diseases - PubMed
    • Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trials - PMC
    •  Myoinositol vs. Metformin in Women with Polycystic Ovary Syndrome: A Randomized Controlled Clinical Trial - PMC
    • The Comparative Effects of Myo-Inositol and Metformin Therapy on the Clinical and Biochemical Parameters of Women of Normal Weight Suffering from Polycystic Ovary Syndrome
    • Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials - PubMed
    • Full article: Comparison of metformin plus myoinositol vs metformin alone in PCOS women undergoing ovulation induction cycles: randomized controlled trial

• The effects of inositol supplementation on lipid profiles among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials

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