Episode Details
Back to EpisodesThe Gary Null Show 1-16-26
Description
- Probiotics emerge as a potent tool against depression and anxiety
- Altered microbiome: Oral bacteria play a role in chronic liver disease, study reveals
- Health issues linked to cosmetic jab complications
- From yoga to awe walks: Many paths lead to better mental health, largest analysis of well-being interventions finds
- Weight loss drugs may cause nutritional deficiencies without proper guidanc
- A major analysis of 23 clinical trials finds probiotics can significantly reduce symptoms of depression and anxiety in clinically diagnosed patients.
- The benefits, appearing within 4-8 weeks, were comparable to some conventional antidepressants but without the same side-effect profile.
- The gut-brain axis, a communication network largely ignored by conventional psychiatry, is central to understanding this connection.
- Single-strain probiotic supplements, particularly certain Lactobacillus and Bifidobacterium species, showed the strongest mental health effects.
- This research supports a holistic view of mental wellness, where gut health is a foundational component of treatment.
Altered microbiome: Oral bacteria play a role in chronic liver disease, study reveals
Technical University Munich (Germany), January 15 2026 (Medical Xpress)
Each year, more than two million people die from advanced chronic liver disease (ACLD). Previous research has linked gut microbiome disruptions to this condition and suggested that bacteria typically found in the mouth may colonize the gut.
A new study published in Nature Microbiology now shows that identical bacterial strains occur in both the mouth and gut of patients with advanced chronic liver disease and also reveals a mechanism by which oral bacteria affect gut health. The researchers also found that this process coincides with worsening liver health.
Researchers analyzed bacterial populations in saliva and stool samples from patients. The team found that both the gut and oral microbiome undergo significant changes as liver disease worsened, where changes to the oral microbiome were already detectable at earlier disease stages.
In healthy individuals, bacterial communities differ substantially between body sites. In patients with liver disease, however, oral and gut microbiomes became increasingly similar as the disease progressed and nearly identical bacterial strains were recovered from the mouth and gut of patients.
"These strains are typically found in the mouth and are rarely present in the healthy gut. However, we observed increases in the absolute abundances of these oral bacteria in patients with advanced chronic liver disease. This strongly suggests that these bacteria translocate from the mouth and colonize the gut," explains Melanie Schirmer, Professor of Translational Microbiome Data Integration at TUM.
Health issues linked to cosme