Episode Details

In this episode of The Skincarma Pod, Carmine sits down with Alisa Lask, CEO of Rion Aesthetics and the medical-grade skincare line Plated Skin Science. Together, they unpack what’s real – and what’s hype – in the fast-emerging world of exosomes in skincare.

Alisa shares her path from Midwest beginnings and a career across Eli Lilly, Allergan, and Galderma, to leading a regenerative aesthetics company built on platelet-derived exosome technology – a category Plated helped bring into the skincare conversation.

Carmine and Alisa dive into:

What exosomes are (Alisa’s simple “text messaging system” explanation);

Why platelet-derived exosomes are fundamentally different from plant-based “exosome” claims;

Plated’s origin story rooted in the Mayo Clinic’s Van Cleve Cardiac Regenerative Medicine Program;

How Plated sources material from FDA-compliant platelet banks (and why transparency matters);

Why Plated is provider-dispensed, not built for big-box beauty retail;

Plus: murder-mystery comfort TV, safari travel, dog rescue, and the lightning-round line you won’t forget: “I feel most like myself when…I’m in the barn.”

Curious about exosomes? Explore Carmine’s article 2025 Ingredient Trends: Exosomes Are One Part Science, One Part Story on Substack here.

Connect with Alisa on Instagram at @alisa.lask_rion and on LinkedIn here. Explore Plated Skin Science on Instagram at @platedskinscience and learn more about the products, exosome science and brand ethos at platedskinscience.com.

Follow Skincarma on Instagram and on TikTok. Catch product reviews of Carmine’s top picks of the best skincare on the Skincarma Blog. You can also connect with Carmine on LinkedIn here and explore his extensive work in beauty on the Carmine Montalto INK website here.

If you enjoyed this episode, please subscribe, rate and/or leave a review on Apple Podcasts, Substack, or Spotify to help Carmine reach more curious listeners.

Product links:

Plated Intense Serum

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