Guest:
Dr. Camila Coelho is a Principal Investigator at the Icahn School of Medicine at Mount Sinai, where her lab studies emerging pathogens. She talks about her lab’s work on mpox and other viruses, her approach to mentorship, and how her MBA education helps her in science. (36:00)
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The Immunology Round Up
Epigenetic Programming of T Cells – Researchers developed an all-RNA platform for efficient, durable and multiplexed epigenetic programming in primary human T cells. (3:57)
Converting Conventional T Cells to Tregs – Using a combination of cytokines and pharmacological approaches, conventional effector T cells can be converted into functional and stable Tregs. (9:40)
A Host–Pathogen Arms Race – E. coli uses the effector NleL to suppress epithelial extrusion, which aids in bacterial spread. (23:06)
Lactation and Lowered Breast Cancer Risk – Parity induces an accumulation of CD8+ T cells in breast tissue, which reduced tumor growth and increased immune cell infiltration in a mouse model. (28:13)
Image courtesy of Dr. Camila Coelho