Season 5 Episode 54
For decades, the message seemed clear: a little alcohol might protect your brain. The famous U-shaped curve suggested light drinkers were safer than both heavy drinkers and non-drinkers when it came to dementia risk.
But what if this reassuring narrative was built on a fundamental misreading of the science?
In this paradigm-shifting episode, we explore a massive study using genetic data from 2.4 million people that completely dismantles the protective drinking myth. Through Mendelian randomization—a powerful technique that uses genetics to establish causation—researchers discovered the U-curve was an illusion created by reverse causation and confounding.
You'll discover:
This is Heliox: Where Evidence Meets Empathy
Independent, moderated, timely, deep, gentle, clinical, global, and community conversations about things that matter. Breathe Easy, we go deep and lightly surface the big ideas.
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Four recurring narratives underlie every episode: boundary dissolution, adaptive complexity, embodied knowledge, and quantum-like uncertainty. These aren’t just philosophical musings but frameworks for understanding our modern world.
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