Podcast Episode Details

015 Training Frequency - Why 3x per week beats 2x even if MYOPS is still elevated

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Episode 16

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In this episode of Hypertrophy: Past and Present, Jake and Chris explore Sig Klein’s early A/B full body routine from the pre-steroid bodybuilding era before examining the claim that elevated myofibrillar protein synthesis blunts the effectiveness of subsequent workouts.

Key topics include:

• Sig Klein’s beginner routine
•  The difference between myofibrillar protein synthesis and hypertrophy stimulus
• What comparing one vs three set studies shows us about elevated synthesis timelines
• Why any overlap effect is small (and irrelevant for single-set workouts)
• Why the weekly net stimulus still favours three times per week over two times per week training

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Published on 2 weeks ago