Guest:
Dr. Jeanne Loring is a Co-Founder of Aspen Neuroscience and Professor Emeritus at Scripps Research. She talks about generating gametes from the functionally extinct northern white rhinoceros, Aspen’s early days and its recent clinical trial results for Parkinson’s cell therapy, and sending her own stem cells into space. She also discusses the need for genetic variation in iPSC lines. (46:23)
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The Stem Cell Science Round Up
Lack of Evidence for Transitional Cerebellar Progenitors – New analysis of single-cell RNA sequencing refutes the existence of transitional cerebellar progenitor cells. (1:50)
Organoid Vascularization – Vascularized organoids resemble human fetal lung and intestine features. (17:05)
Metabolic Profiling of HSPCs – Researchers presented the integrated metabolome, lipidome, and transcriptome of human adult HSPCs upon differentiation, aging, and acute myeloid leukemia. (28:40)
Blood Vessels in Liver Organoids – Scientists generated liver organoids that contain fully perfused human vessels with functional sinusoid-like features. (37:00)
Image courtesy of Dr. Jeanne Loring