In this explosive and highly anticipated episode, Dr. Roger McFillin hosts Dr. Ragy Girgis, a Columbia University Professor of Psychiatry and researcher, for a no-holds-barred confrontation that exposes the shocking divisions tearing apart the mental health field. What begins as a conversation about mass violence research rapidly explodes into a devastating examination of psychiatric medicine's crumbling foundations, questionable effectiveness, and devastating potential harms. The two clash in fierce, unrelenting disagreements over fundamental issues including the validity of DSM diagnoses, the debunked "chemical imbalance" theory of depression, dangerous SSRI safety cover-ups and black box warnings, corrupted research quality and pharmaceutical industry manipulation, and the catastrophic crisis of psychiatric drug overprescription poisoning 1 in 4-5 Americans. Dr. Girgis desperately defends traditional academic psychiatry and current treatment approaches, while Dr. McFillin ruthlessly dismantles the entire paradigm, arguing that the current system is systematically creating chronic mental illness rather than healing it. Buckle up for this brutal intellectual warfare.
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Throughout the interview, Dr. Girgis repeatedly stated that "the data is clear" while dismissing contradictory evidence that challenges his conclusions. For our listeners' benefit, I have compiled research and documentation that directly disputes several of Dr. Girgis's key claims.
Serotonin Hypothesis of Depression
1. The serotonin theory of depression: a systematic umbrella review of the evidence (Moncrieff et al.)
Conclusions: "This review suggests that the huge research effort based on the serotonin hypothesis has NOT produced convincing evidence of a biochemical basis to depression. This is consistent with research on many other biological markers . We suggest it is time to acknowledge that the serotonin theory of depression is NOT empirically substantiated."
2.What has serotonin to do with depression?
Conclusions: "Simple biochemical theories that link low levels of serotonin with depressed mood are no longer tenable."
3. Is the chemical imbalance an ‘urban legend’? An exploration of the status of the serotonin theory of depression in the scientific literature
Violence & Suicide Associated with SSRI's
1. Precursors to suicidality and violence on antidepressants: systematic review of trials in adult healthy volunteers
2. Prescription Drugs Associated with Reports of Violence Towards Others
3. Antidepressant-induced akathisia-related homicides associated with diminishing mutations in metabolizing genes of the CYP450 family
4. Lexapro Approved for Pediatric Use Despite the 6-Fold Increase in Suicide Risk
5. McFillin Substack Review on Lexapro approved despite Suicide Risk
6. Suicidality and aggression during antidepressant treatment: systematic review and meta-analyses based on clinical study reports
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Published on 1 month, 3 weeks ago
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