Podcast Episode Details

How to Reverse Biological Age, Balance Hormones & Slow Down Ageing—The Power of Glycans for Women’s Health | Nikolina Lauc

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Episode 464

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What if you could measure how fast your immune system is ageing—and actually reverse it? In this groundbreaking episode, I sit down with Nikolina Lauc, CEO and co-founder of GlycanAge, to unpack the science behind one of the most accurate biological age tests available today. We explore how lifestyle, hormones, and stress directly impact your biological age—and how you can use cutting-edge science to turn back the clock.

You'll discover how oestrogen therapy, moderate exercise, and even small tweaks like swapping HIIT for yoga could potentially lower your biological age by up to 15 years. Plus, I share my personal GlycanAge results and the exact changes I'm making to optimise my health span. If you’re serious about proactive, data-driven health, this is a must-listen!

 

KEY TAKEAWAYS:

• Glycans as Aging Markers: Glycans reflect the state of your immune system and offer early warning signs for chronic disease years before symptoms appear.

• Men vs Women’s Aging Patterns: Women experience a rapid biological ageing spike during perimenopause and menopause linked to oestrogen decline.

• Impact of Stress on Aging: Chronic psychological stress can accelerate biological ageing by up to 15 years—more than menopause itself.

• Hormone Therapy Benefits: Starting oestrogen therapy around menopause can lower biological age by up to 10 years and reduce all-cause mortality by 40%.

• Exercise Personalisation Matters: Moderate exercise supports longevity, but overtraining—especially in women—can accelerate ageing.

• Lifestyle Tweaks Make a Big Difference: Small changes, like replacing high-intensity workouts with yoga, reduced one client's biological age by 15 years in 12 weeks.

• Supplements and GlycanAge: NAD+ boosters and omega-3 enriched foods show promising effects, but personalised interventions work best.

 

TIMESTAMPS AND KEY TOPICS:

1:26 - What are glycans and how they influence ageing

5:23 - Glycans vs telomere and epigenetic tests (accuracy differences)

10:57 - Problems with biological age testing noise

14:41 - The role of hormones in biological ageing

18:30 - How fast lifestyle changes can impact your biological age

22:57 - Why fasting and overtraining may hurt women’s health

27:11 - Personalising exercise to slow ageing

34:00 - Case study: How swapping HIIT for yoga reversed 15 years of biological ageing

40:18 - Angela’s personal GlycanAge test results

48:07 - How often you should test and what to change first

53:06 - The connection between sleep and your immune age

 

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