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Ever feel like you're navigating a biological minefield? 

We delve into the unsettling truth about COVID-19's long shadow: its insidious impact on our delicate endocrine system. Forget the simplistic headlines; we're going deep into the molecular mechanisms that reveal how this virus throws our hormones into disarray.

We'll unpack the strange phenomenon of elevated cortisol levels and the perplexing "pseudo-Cushing's syndrome". More disturbingly, we'll explore how COVID-19 can trigger endocrine resistance, making our bodies less responsive to vital hormonal signals. 

Discover the differing pathways at play in mild versus severe cases, with EGFR and MMP9 in milder infections and IGF-1R and NOTCH signalling taking center stage in the severe. 

We’ll also dissect the crucial roles of GNAS and calcium dysregulation in this hormonal havoc. This isn't about fear-mongering; it's about understanding the intricate ways this virus rewrites our internal landscape and what it means for long-term health and future treatments.

Endocrine dysregulation in COVID-19: molecular mechanisms and insights

This is Heliox: Where Evidence Meets Empathy

Independent, moderated, timely, deep, gentle, clinical, global, and community conversations about things that matter.  Breathe Easy, we go deep and lightly surface the big ideas.

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Disclosure: This podcast uses AI-generated synthetic voices for a material portion of the audio content, in line with Apple Podcasts guidelines. 

We make rigorous science accessible, accurate, and unforgettable.

Produced by Michelle Bruecker and Scott Bleackley, it features reviews of emerging research and ideas from leading thinkers, curated under our creative direction with AI assistance for voice, imagery, and composition. Systemic voices and illustrative images of people are representative tools, not depictions of specific individuals.

We dive deep into peer-reviewed research, pre-prints, and major scientific works—then bring them to life through the stories of the researchers themselves. Complex ideas become clear. Obscure discoveries become conversation starters. And you walk away understanding not just what scientists discovered, but why it matters and how they got there.

Independent, moderated, timely, deep, gentle, clinical, global, and community conversations about things that matter.  Breathe Easy, we go deep and lightly surface the big ideas.

Spoken word, short and sweet, with rhythm and a catchy beat.
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