Episode Details

This episode dives into the rare Whipple's disease, focusing on the articular manifestations of this infectious masquerader and when a rheumatologist should consider it in the differential.

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• Intro :20
• In this episode :28
• Background on the organism 5:25
• An important point when making the diagnosis 7:48
• Who gets infected? 8:55
• What is Whipple's disease? 11:48
• This disease is fatal 15:53
• A look at the joints 16:28
• What happens when you give these patients immunosuppression? 26:36
• How to diagnose 28:38
• Summary so far 31:00

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• Other organ manifestations of Whipple's disease 32:08
• Summary and take-home 44:36

Disclosure: Brown reports no relevant financial disclosures.

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References:

Bousbia S, et al. Emerg Infect Dis. 2010;16:258-63.

Chan RY, et al. Ophthalmology. 2001;108:2225-2231.

Dobbins 3rd WO, et al. Arthritis Rheum. 1987;30:102-105.

Durand DV, et al. Medicine (Baltimore). 1997;76:170-84.

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