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Ep. 80: “Gene Therapy in a Box” Featuring Dr. Jen Adair

Published 9 years, 7 months ago
Description

Guest:

Dr. Jen Adair, assistant member of the clinical research division at the Fred Hutch Cancer Research Center, and Assistant Professor of Medical Oncology at the University of Washington School of Medicine. Adair’s group investigates retrovirus-based gene transfer into hematopoietic stem cells as a viable treatment for genetic, malignant and infectious diseases.

Resources and Links

Dogs Form Memories of Experiences – This article suggests that dogs possess some version of episodic memory, which allows them to recall personal experiences, and not just simple associations between, for instance, sitting and getting a treat.

Lower Social Status Can Alter the Immune System – A new study manipulating the pecking order of monkeys finds that low social status kicks the immune system into high gear, leading to unwanted inflammation akin to that in people with chronic diseases.

A New Fetal Genome Test – This article reports that by doing a Pap smear as early as five weeks into a pregnancy, researchers can collect enough fetal cells to test for abnormalities linked to more than 6,000 genetic disorders.

Old Blood Carries Risks for Brain – This article reveals that after transfusions of young blood, old mice still had lower numbers of newborn nerve cells in the hippocampus, a brain structure important for learning and memory.

Synthetic Recording and In Situ Readout of Lineage Information in Single Cells – Researchers developed a new method for reading the history and “family trees” of cells called MEMOIR (Memory by Engineered Mutagenesis with Optical In Situ Readout), which can record the life history of animal cells, their relationships with other cells, communication patterns, and the influential events that have shaped them.

Take a Journey into the Center of a Stem Cell – Scientists journeyed to the center of a stem cell that’s maturing into a nerve cell using a powerful X-ray microscope to snap pictures of stem cells at different stages of differentiation.

Neural Progenitors F

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