Episode Details

The Filtrate:

Joel Topf

Swapnil Hiremath

Nayan Arora

Sophie Ambruso

And special guests:

Jay L Koyner, Professor of Medicine, University of Chicago

Sarah Faubel, Professor of Medicine, University of Colorado

Editor

Nayan Arora

Show Notes:

It was Kidney 360, not Kidney Medicine. Here is the study I was thinking of: https://kidney360.asnjournals.org/content/2/1/33

SNL Five-Timers Club: https://www.youtube.com/watch?v=6bWGoWFMwKE

The Fluid and Electrolyte Companion. Download The Whole Enchilada

About the Authors from Topf and Faubel’s first book, The Microbiology Companion.

Ted Post: The Sarah Faubel of The Clinical Physiology of Acid Base and Electrolyte Disorders.

Meta analysis of early dialysis in AKI by Victor Seabra: https://pubmed.ncbi.nlm.nih.gov/18562058/

Meta analysis of early dialysis in AKI by Morgan Grimes: https://www.ajkd.org/article/S0272-6386(15)00530-2/abstract

H-index: https://en.wikipedia.org/wiki/H-index

Mortality in ARDS: ACURASYS study. The hazard ratio for death at 90 days in the cisatracurium group, as compared with the placebo group, was 0.68 https://www.nejm.org/doi/full/10.1056/nejmoa1005372

Has Mortality from Acute Respiratory Distress Syndrome Decreased over Time? A Systematic Review

It is commonly stated and assumed that mortality from acute respiratory distress syndrome (ARDS) is decreasing.

We found that mortality from ARDS has not decreased substantially since the publication of a consensus definition in 1994. Based on our findings, a baseline mortality risk from ARDS of 40 to 45% for observational studies and 35 to 40% for randomized control trials should be expected. These results highlight the need for future effective therapeutic interventions for this highly lethal syndrome.

https://www.atsjournals.org/doi/full/10.1164/rccm.200805-722oc

From Up To Date:

Numerous studies suggest that survival has improved over time [2,9,10,

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