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Two factors:

Range of Motion – how much knee flexion you allow

Tension – how much tension you are putting through the quad, connective tissue of the knee

Progression

Progress ROM first, then tension 

0 – no ROM, no tension 
Zone 1-2 Biking 
Daily

1 – some ROM, micro tension
Reverse sled drag / backwards walking
Daily

2 – full ROM, mini tension
Heel sits 
Daily

3 – full ROM, low tension
Front foot elevated, knees over toes split squat
Banded cyclist squats
Banded sissy squats
2-3x per week

4 – full ROM, moderate tension
KOT split squat
Cyclist squat
2x per week

5 – full ROM, high tension
20-15-10-5-1 Reps
1-2x per week 

Common mistakes

1. Avoidance – avoiding using the knee altogether

2. Assuming it will heal completely with rest. 0 to 60 – “I just need to rest it.” Going from complete rest to full ROM, high tension. 

3. Not enough frequency – micro and mini tension needs to be daily 

4. Stopping movement prep/accessories altogether once the knee feels good. Keep one step down from wherever you are in the progression in your program if you’ve experienced knee pain in the past.