Episode Details

Prof. Patrick Küry talks about treating neurodegeneration in Multiple Sclerosis by modulating HERV-W and binding to its envelope protein.

You can read the questions and short answers on my blog: https://ms-perspektive.com/33-patrick_kuery

This time I talk to Prof. Dr. Patrick Küry about whether we can treat neurodegeneration in multiple sclerosis by modulating HERV-W?

Multiple sclerosis is driven by two disease-causing aspects – acute inflammatory activity, which is now well treatable, and neurodegeneration, which continues to pose major challenges to researchers and physicians. Finding ways to effectively treat neurodegeneration could finally help people in the progressive course, whether PPMS or SPMS. And since neurodegeneration presumably starts in the prodromal phase, i.e., with the onset of pathogenic processes, all MS patients would benefit. But what is HERV-W and how can it be influenced to prevent neurodegeneration? That's what I talk about in an interview with Prof. Küry.

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• Introduction – Who is Prof. Dr. Patrick Küry?
• Neurodegeneration in multiple sclerosis
• Role of HERV-W in multiple sclerosis
• Future outlook to stop neurodegeneration in MS
• Farewell

Introduction – Who is Prof. Dr. Patrick Küry?

Molecular and cellular biologist, Swiss origin, PhD in Switzerland, postdoctoral education in UK on developmental neurobiology, moved to Düsseldorf, Germany for cellular studies on regeneration of the nervous system.

Prof. for Neuroregeneration in Düsseldorf, working in a clinical environment, connecting basic science with clinical applications, research team consisting of basic scientists and medical scientists.

Trained as biologist, I love zoology, being in the field, in the nature, in the desert…

Photo: Dr. Rok Humar

How and where can interested people follow your research activities?

• Email: kuery@hhu.de
• Website: https://www.uniklinik-duesseldorf.de/patienten-besucher/klinikeninstitutezentren/klinik-fuer-neurologie/forschung/neuroregeneration-kuery
• PubMed
• X (twitter): @HERV&Brain
• https://geneuro.com

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I find this research on HERV-W extremely exciting, especially since it seems so far that there are no or few side effects to be expected. And I would be so very happy if there are finally first breakthroughs in the treatment of neurodegeneration and thus the progressive processes of MS. So that people with PPMS and SPMS have more than symptomatic therapy options available. I am interested in your opinion on this. Feel free to contact me and