Episode Details

Dr. Markley Silva Oliveira Jr. has done research on astrocytes and how they can contribute to better myelin repair for PwMS using Medrysone.

You can find the full transcript to read on the corresponding blog article: https://ms-perspektive.com/024-research-on-myelin-repair

Episode 23 is about an exciting research work on myelin repair in the progressive course of MS with the help of astrocyte cells that contribute to it under administration of Medrysone, a corticosteroid.

My interview guest is Dr. Markley Silva Oliveira Junior, who wrote his doctoral thesis on this topic at Heinrich Heine University in Düsseldorf. It didn't stop at writing alone, though; Markley did a lot of experimentation and found amazing things about astrocytes, whose impact used to be viewed rather negatively, but which make a crucial contribution to repair.

And since Medrysone is already an approved drug in the field of ophthalmology, it could go faster with the approval, if the successful results from animal experiments, are equally good for humans.

This episode was originally recorded for the German MS-Perspektive podcast in May 2023. As I feel, it is emotionally helpful to hear about research on myelin repair every now and then, I decided to publish it again for the international MS-Perspektive podcast.

The podcast and blog post are also available in German.

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• Introduction of Dr. Markley Silva Oliveira-Junior
• Mechanism of myelin repair in MS-patients
• The effect of corticosteroid medrysone on the myelin repair in MS-patients
• Farewell

Introduction of Dr. Markley Silva Oliveira-Junior

Hi everyone. Just glad to be here in invitation from Nele, many thanks for having me. Well, I'm a very honored Brazilian guy, neuroscientist, married, I love a good hiking, travelling, good food (quite spoiled I am for being Brazilian, but France and Italy have my heart on that) and of course hangout with my friends and family.

How and where can interested people follow the most recent research activities?

In my LinkedIn I'm always sharing things that I found interesting about research. Sometimes, I do my own posts, otherwise I'm sharing what I think is interesting there. For me, if you're interested in MS, for example, the MS UK portal is one of the key ones to be looking into, if you are a layperson or if you are an expert. You can get things regarding to that. As a scientist, my key portal to be looking into is basically PubMed, but if you want to know more about what I'm doing, my LinkedIn is actually the best recommendation that I can do to follow what I've been working with. For example, I'm planning to do a post next week, where I will address a little bit more what I'