Episode Details

Learn about octopi forming communities, clues to the origins of schizophrenia, and a new compound giving researchers hope for fighting tough to treat cancers.   

Octopus Culture 

• “Hidden World of Octopus Cities and Culture Shows why it’s Wrong to Farm These Sentient Creatures” by Guardian Magazine
  • https://www.guardianmag.press/2022/04/hidden-world-of-octopus-cities-and-culture-shows-why-its-wrong-to-farm-these-sentient-creatures.html/
• “The question of animal emotions” by Frans B. M. De Waal and Kristin Andrews
  • https://doi.org/10.1126/science.abo2378
• “Why octopuses are building small “cities” off the coast of Australia” by Annalee Newitz
  • https://arstechnica.com/science/2017/09/why-octopuses-are-building-small-cities-off-the-coast-of-australia/
• “A second site occupied by Octopus tetricus at high densities, with notes on their ecology and behavior” by David Scheel, et al.
  • https://doi.org/10.1080/10236244.2017.1369851
• Animal Culture by Zhana Reznikova
  • https://doi.org/10.1007/978-1-4419-1428-6_745

Schizophrenia Origins

• “Landmark Study Reveals Clearest Genetic Signals Yet for Schizophrenia Risk” by Rutgers Research
  • https://research.rutgers.edu/news/landmark-study-reveals-clearest-genetic-signals-yet-schizophrenia-risk
• “Mapping genomic loci implicates genes and synaptic biology in schizophrenia” by Vassily Trubetskoy, et al.
  • https://doi.org/10.1038/s41586-022-04434-5
• “What is Schizophrenia?” by The American Psychiatric Association
  • https://psychiatry.org/patients-families/schizophrenia/what-is-schizophrenia
• “What is a Gene?” by Medline Plus
  • https://medlineplus.gov/genetics/understanding/basics/gene/#:~:text=A%20gene%20is%20the%20basic,more%20than%202%20million%20bases

Killing Cancer 

• “Promising Compound Kills Range Of Hard-To-Treat Cancers By Targeting A Previously Undiscovered Vulnerability” by UT Southwestern Medical Center
  • https://www.utsouthwestern.edu/newsroom/articles/year-2022/hard-to-treat-cancers.html
• “Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress” by Xihui Liu, Suryavathi Viswanadhapalli, Shourya Kumar, Tae-Kyung Lee, Andrew Moore, Shihong Ma, Liping Chen, Michael Hsieh, Mengxing Li, Gangadhara R. Sareddy, Karla Parra, Eliot B. Blatt, Tanner C. Reese, Yuting Zhao, Annabel Chang, Hui Yan, Zhenming Xu, Uday P. Pratap, Zexuan Liu, Carlos M. Roggero, Zhenqiu Tan, Susan T. Weintraub, Yan Peng, Rajeshwar R. Tekmal, Carlos L. Arteaga, Jennifer Lippincott-Schwartz, Ratna K. Vadlamudi, Jung-Mo Ahn & Ganesh V. Raj.
  • https://www.nature.com/articles/s43018-022-00389-8
• “Scientists Discover New Molecule That Kills Hard-to-Treat Cancers” By Amanda Siegfried
  • https://news.utdallas.edu/health-medicine/new-molecule-cancer-cell-killer-2022/

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Find episode transcripts here: https://curiosity-daily-4e53644e.simplecast.com/episodes/octopus-culture-schizophrenia-origins-killing-cancer