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Matt Begemann: The Cancer-Killing CRISPR
Matt Begemann: The Cancer-Killing CRISPR

Episode 52

What began as a search for plant-friendly CRISPR tools led Matt Begemann, PhD, and colleagues to Cas12a2, or CasCLEAR, an unusual system that can tri…

3 hours ago

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Wei-Wu He: Craig Venter’s Legacy and the Future of Human Longevity
Wei-Wu He: Craig Venter’s Legacy and the Future of Human Longevity

Episode 51

Human Longevity executive chairman Wei-Wu He discusses how the integration of genomics, advanced imaging, and artificial intelligence could transform…

2 weeks ago

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Palani Kumaresan: Roche Diagnostics Is Ramping Up—Should Illumina Be Worried?
Palani Kumaresan: Roche Diagnostics Is Ramping Up—Should Illumina Be Worried?

Episode 50

Roche’s AXELIOS sequencer, Alzheimer’s blood test, and push to automate mass spectrometry point to a broader strategy of making advanced diagnostics …

4 weeks ago

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Ken Greenberg: Can Ultrasound Shatter the Gene Therapy Delivery Bottleneck?
Ken Greenberg: Can Ultrasound Shatter the Gene Therapy Delivery Bottleneck?

Episode 49

Gene therapy’s biggest bottleneck remains delivery: getting increasingly sophisticated genetic medicines safely into the right cells. SonoThera is ta…

1 month, 1 week ago

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David Thaisrivongs: Goldilocks and the First Oral PCSK9 Inhibitor
David Thaisrivongs: Goldilocks and the First Oral PCSK9 Inhibitor

Episode 48

Biocatalysis has evolved from a scientific curiosity into a powerful manufacturing platform, culminating in enlicitide, the first oral macrocyclic pe…

1 month, 3 weeks ago

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Beaubrun and Acharya: No Antibiotic Without a Diagnostic
Beaubrun and Acharya: No Antibiotic Without a Diagnostic

Episode 47

Antimicrobial resistance (AMR) isn't going to be solved by new antibiotics alone—it also requires identifying resistant infections quickly enough to …

2 months, 1 week ago

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Amit Etkin: Precision Psychiatry’s Future Isn’t Genomics—It’s Brain Activity
Amit Etkin: Precision Psychiatry’s Future Isn’t Genomics—It’s Brain Activity

Episode 46

For decades, psychiatry has relied on symptom-based diagnosis and trial-and-error treatment, but precision medicine is set to transform mental health…

2 months, 3 weeks ago

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Michael Antonov: From Virtual World Builder to Real-World Drug Designer
Michael Antonov: From Virtual World Builder to Real-World Drug Designer

Episode 45

AI is transforming biomedical research, but meaningful advances in drug discovery require more than just increasingly powerful algorithms—they depend…

3 months ago

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Philippe Pouletty: Turning Europe’s Life Science Startups Into World Leaders
Philippe Pouletty: Turning Europe’s Life Science Startups Into World Leaders

Episode 44

Philippe Pouletty, MD, is one of Europe’s most successful life sciences entrepreneurs, having spent more than 30 years building category-leading biot…

3 months, 2 weeks ago

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Arthur Caplan: The Right to Life, Liberty, and Pursuit of Health
Arthur Caplan: The Right to Life, Liberty, and Pursuit of Health

Episode 43

While growing up during the polio era, Arthur Caplan, PhD, saw doctors hide painful truths from families and children, which sparked his lifelong que…

4 months ago

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