Podcast Episodes

Nobel Prizes Announced and Breakthroughs for Huntington’s and Rare Diseases

Episode 36

Metal-organic frameworks and peripheral immune tolerance were the big winners of the Nobel prizes in chemistry, and in physiology or medicine, respectively. In this episode of the podcast, we discuss…

Published on 9 hours ago

BPI 2025 Debrief and Takeaways

Episode 35

GEN has been at the forefront of biotech and bioprocessing news for over 40 years. Last week, editor in chief, John Sterling and deputy editor in chief, Julianna LeMieux, PhD, attended BioProcess Int…

Published on 2 weeks ago

Developing New Therapies Through Partnership, Electricity, and Immunotherapy

Episode 34

Novartis has agreed to license and develop Arrowhead Pharmaceuticals’ preclinical stage small interfering RNA (siRNA) therapy ARO-SNCA, a potential treatment for Parkinson’s disease and other synucle…

Published on 1 month ago

Stem Cells in Space and AI for Nanoparticles and Peptide Design

Episode 33

This week’s episode explores two frontiers: space travel and artificial intelligence. First, we discuss a study testing whether mouse sperm cryopreserved and stored in the International Space Station…

Published on 1 month, 2 weeks ago

Reversing Parkinson’s in Mice, Protecting Primates from HIV, Top 10 Biotech Clusters, and Sarepta

Episode 32

This episode of GEN's Touching Base spotlights the unexpected relationship between breathing low oxygen and restoration of neuron function in a mouse model of Parkinson’s disease. In addition, a sing…

Published on 2 months ago

Sarepta Under Scrutiny, AstraZeneca’s Big Bet, and AI vs. IDRs

Episode 31

Sarepta has temporarily paused shipments of Elevidys, its FDA-approved treatment for Duchenne muscular dystrophy. In this episode of GEN's Touching Base, we discuss the company’s response to the trag…

Published on 2 months, 2 weeks ago

Merck Acquires Verona, Virtual Cell Challenge, Gene Therapy Restores Hearing

Episode 30

Merck & Co. has acquired Verona Pharma for $10 billion in a deal designed to expand the pharma giant’s portfolio of cardio-pulmonary disease treatments. In a step toward virtual cell benchmarking, th…

Published on 2 months, 4 weeks ago

BIO 2025, Huge Virtual Cell Dataset, AI-Designed De Novo Proteins

Episode 29

Acast

BIO 2025, Huge Virtual Cell Dataset, AI-Designed De Novo Proteins

BIO 2025 is off and running. GEN editors discuss the size and scope of the bustling conference hall and share excitement about th…

Published on 3 months, 3 weeks ago

Rocket’s Gene Therapy Trial Paused, Boltz-2 Open Source, Plasma Swap Rewinds Aging

Episode 28

A gene therapy clinical trial for Danon disease run by Rocket Pharmaceuticals has been suspended following the death of a patient. MIT and Recursion have released Boltz-2, an open-source tool that pr…

Published on 4 months ago

Customized CRISPR for KJ, 10x and Illumina Lawsuits, Regeneron Bags 23andMe

Episode 27

A baby, named KJ, has become the first patient to be treated with a personalized CRISPR therapy to address a severe metabolic disorder. We discuss this story—one of the biggest science/medical storie…

Published on 4 months, 2 weeks ago