JAMA October 2026 Advance Care Planning for Black and White Older Adults With Serious Illness The EQUAL ACP Randomized Trial

The EQUAL ACP randomized trial investigated whether facilitated advance care planning outperforms self-guided methods for seriously ill older adults.…

15 hours ago

JAMA October 2026 Nicotinamide Riboside for Patients With Early-Stage Parkinson Disease The NOPARK Randomized Clinical Trial

A recent phase 3 clinical trial investigated whether the supplement nicotinamide riboside could slow the progression of early-stage Parkinson disease…

16 hours ago

NEJM 10 8 2026 Vasopressors or Fluids in Early Septic Shock

Vasopressors or Fluids in Early Septic Shock

16 hours ago

NEJM 10 8 2026 Effect of Screening with Multicancer Early-Detection Test on Late-Stage Cancer Diagnosis

Effect of Screening with Multicancer Early-Detection Test on Late-Stage Cancer Diagnosis

17 hours ago

NEJM 10 8 2026 Tricuspid-Valve Intervention in Heart Failure

Researchers conducted a clinical trial to determine whether transcatheter tricuspid-valve repair could improve health outcomes for older adults suffe…

17 hours ago

NEJM 10 1 2026 Giredestrant plus Everolimus in Advanced Breast Cancer

Giredestrant plus Everolimus in Advanced Breast Cancer

2 days, 16 hours ago

NEJM 10 1 2026 Obexelimab for the Treatment of IgG4-Related Disease

A recent phase 3 clinical trial investigated obexelimab, a novel monoclonal antibody that suppresses B-cell function without destroying the cells, as…

2 days, 16 hours ago

NEJM 10 1 2026 Atorvastatin, Cardiovascular Events, and Disability-free Survival in Older Adults

Atorvastatin, Cardiovascular Events, and Disability-free Survival in Older Adults

2 days, 16 hours ago

JAMA 9 2026Intrauterine Mepivacaine Instillation vs Placebo for Pain During IUD Placement A Randomized Clinical Trial

This clinical study investigates whether applying a local anesthetic directly into the uterus can alleviate the discomfort typically associated with …

2 weeks, 1 day ago

JAMA 9 2026 Medicare Advantage Enrollment and Access to Kidney Transplant After the 21st Century Cures Act

This retrospective study evaluates whether the expansion of Medicare Advantage eligibility for patients with end-stage kidney disease has impacted th…

2 weeks, 1 day ago