Podcast Episodes

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🔬Causal Models Need Causal Data - Xaira’s X-Cell model for Drug Discovery (Bo Wang & Ci Chu, Chief Discovery Officer & Chief AI Scientist)
🔬Causal Models Need Causal Data - Xaira’s X-Cell model for Drug Discovery (Bo Wang & Ci Chu, Chief Discovery Officer & Chief AI Scientist)

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If test loss flatlines after 1.5B parameters while training loss continues to drop as you scale, that tells you that your model is …

9 hours ago

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🔬 The Lab of the Future Should Feel Like a Data Center — Andy Beam & Rafa Gómez-Bombarelli, Lila Sciences
🔬 The Lab of the Future Should Feel Like a Data Center — Andy Beam & Rafa Gómez-Bombarelli, Lila Sciences

Imagine a dark warehouse. Racks and racks of devices with wires, tubes, and electronics sticking out. The next AI data center? No. This is Lila Scien…

5 days, 15 hours ago

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Why AI Infrastructure must evolve for Agent Experience — Akshat Bubna, Modal CTO
Why AI Infrastructure must evolve for Agent Experience — Akshat Bubna, Modal CTO

We’ve been running a bit of an Agent Cloud series surveying all the top inference/compute/cloud providers, from Databricks to Daytona to Railway and,…

1 week, 6 days ago

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🔬 The Coolest Diffusion Research Isn't in LLMs — Evan Feinberg & Sergey Edunov, Genesis Molecular AI
🔬 The Coolest Diffusion Research Isn't in LLMs — Evan Feinberg & Sergey Edunov, Genesis Molecular AI

This episode has a fun personal twist: There’s a counterfactual world where I was employee #1 at Genesis Molecular AI, the company behind today’s ep…

2 weeks, 6 days ago

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Why the Frontier Ecosystem must be Open — Matei Zaharia and Reynold Xin, Databricks
Why the Frontier Ecosystem must be Open — Matei Zaharia and Reynold Xin, Databricks

We’re excited to have Databricks join us at AIEWF, among hundreds of the top companies in the AI Engineer ecosystem. LS subscribers can use their dis…

3 weeks, 6 days ago

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Red-Teaming after Mythos — Zico Kolter & Matt Fredrikson, Gray Swan
Red-Teaming after Mythos — Zico Kolter & Matt Fredrikson, Gray Swan

AI Engineer World’s Fair regular bird tix will sell out ~today! Join us next week ahead of the Late Bird price hike and get >$40,000 in sponsor credi…

4 weeks, 1 day ago

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The Professor of Outputmaxxing — Anjney Midha, AMP
The Professor of Outputmaxxing — Anjney Midha, AMP

Last 4 days before regular tickets sell out at AI Engineer World’s Fair - this is the single biggest gathering of AI Engineers, Founders, Leaders, an…

1 month ago

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🔬 The Self-Driving Lab — Joseph Krause, Radical AI
🔬 The Self-Driving Lab — Joseph Krause, Radical AI

On the Science pod, we’ve been covering a lot of the ground on how AI is revolutionizing STEM, but one of our favorite off the record topics since ou…

1 month ago

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Reality: The Final Eval — Lukas Petersson and Axel Backlund of Andon Labs
Reality: The Final Eval — Lukas Petersson and Axel Backlund of Andon Labs

The new AIEWF website is live! Get your tickets booked ASAP as they -will- sell out. Take the AI Engineering Survey and get >$2k in credits and free …

1 month, 2 weeks ago

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🔬Scaling Past Informal AI - Carina Hong, Axiom Math
🔬Scaling Past Informal AI - Carina Hong, Axiom Math

In 2025, seven-month-old startup Axiom solved all 12 of the problems Putnam exam (scoring 8/12 in the time limit) a prestigious undergraduate math ex…

1 month, 2 weeks ago

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