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A New Operating System for Physicians with OpenEvidence Founder Daniel Nadler


Season 1 Episode 130


How does a new technology get adopted by 40% of American doctors in just 18 months? In an era where the golden age of biotechnology has also created a dark age of physician burnout, OpenEvidence foun…


Published on 1 day, 8 hours ago

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Reshaping America’s Economy for the Superintelligence Century with Jacob Helberg



AI doomers say that the technology will be the ultimate job-killer. But Jacob Helberg wants people to see AI as a tech that will boost, not replace, human workers and give them superpowers. Under Sec…


Published on 1 week, 2 days ago

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How Agentic AI is Transforming The Startup Landscape with Andrew Ng



Andrew Ng has always been at the bleeding edge of fast-evolving AI technologies, founding companies and projects like Google Brain, AI Fund, and DeepLearning.AI. So he knows better than anyone that f…


Published on 2 weeks, 2 days ago

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Chips, Neoclouds, and the Quest for AI Dominance with SemiAnalysis Founder and CEO Dylan Patel


Season 1 Episode 127


What would it take to challenge Nvidia? SemiAnalysis Founder and CEO Dylan Patel joins Sarah Guo to answer this and other topical questions around the current state of AI infrastructure. Together, th…


Published on 3 weeks, 2 days ago

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The Shifting Value of Content in the AI Age with Cloudflare CEO Matthew Prince



Cloudflare has spent nearly fifteen years making the Internet faster, more reliable, and more secure. So now that AI systems are changing the way we interact with the Internet, Cloudflare wants to he…


Published on 4 weeks, 2 days ago

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America’s Plan to Dominate the Full AI Stack with Sriram Krishnan


Season 1 Episode 125


Sriram Krishnan was never interested in policy. But after seeing a gap in AI knowledge at senior levels of government, he decided to lend his expertise to the tech-friendly Trump administration. Seni…


Published on 1 month ago

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The Power of Quality Human Data with SurgeAI Founder and CEO Edwin Chen


Season 1 Episode 124


In the generative AI revolution, quality data is a valuable commodity. But not all data is created equally. Sarah Guo and Elad Gil sit down with SurgeAI founder and CEO Edwin Chen to discuss the mean…


Published on 1 month, 1 week ago

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Asimov: Building An Omniscient RL Oracle with ReflectionAI’s Misha Laskin


Season 1 Episode 123


Superintelligence, at least in an academic sense, has already been achieved. But Misha Laskin thinks that the next step towards artificial superintelligence, or ASI, should look both more user and pr…


Published on 1 month, 2 weeks ago

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Why Platforms Win and Point Solutions Fail with Rippling CEO Parker Conrad



As a three-time founder, Parker Conrad has one piece of advice for aspiring entrepreneurs—don’t do it. The Rippling co-founder and CEO joins Sarah Guo to talk about what he learned from the crash at …


Published on 1 month, 3 weeks ago

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Chai-2: The AI Model Accelerating Drug Discovery with Chai Discovery Co-Founders Jack Dent and Joshua Meier



AI has already fueled breakthroughs in biotechnology—but now, further advances in AI are poised to fuel pharmaceutical discoveries as well. Sarah Guo sits down with Joshua Meier and Jack Dent, co-fou…


Published on 2 months ago





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