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E126: Risk Signals, JAKs, and SELECTIVE-ity


Episode 127


Covering an interesting but ultimately disappointing post hoc study of multiple upadacitinib trials in RA. Initially some hope for clarity in the "Do JAKs cause all the badness?" questions, but ultim…


Published on 1 day, 7 hours ago

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E125: Adrenal Insufficiency after Stopping Prednisone


Episode 126


Interesting read this week - I cover a nifty little paper that presented data about adrenal insufficiency after stopping prednisolone, published in JAMA Open in March 2025.  

 

Open Access Journal He…


Published on 2 months, 1 week ago

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e124: MTX vs Pred for Pulmonary Sarcoidosis: PREDMETH Study


Episode 125


Interesting NEJM trial this week comparing methotrexate to prednisone for pulmonary sarcoidosis.

Paper available here: https://www.nejm.org/doi/full/10.1056/NEJMoa2501443 


Published on 2 months, 4 weeks ago

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E123: Upadacitinib for Giant Cell Arteritis: SELECT-GCA


Episode 124


Podcast this week about the recently published SELECT-GCA study, which evaluated the use of the janus kinase inhibitor upadacitinib (Rinvoq) for patients with new and relapsing GCA. Successful trial …


Published on 4 months, 1 week ago

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E122: Guidelines for Maybe Diagnosing HLH


Episode 123


This week I cover another of my newsletters, though I mostly use it as a skeleton to riff on a common (and challenging) issue for rheumatology consultants; diagnosing HLH. Check out the guidelines th…


Published on 4 months, 3 weeks ago

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E121: Obinutuzumab in SLE-LN


Episode 122


Another day, another b cell podcast. Seems to be all the rage! This week I discuss the recently published NEJM trial of the anti CD20 agent obinutuzumab in lupus nephritis. Worth a read and listen, p…


Published on 5 months, 1 week ago

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E120: Real Life Use of PEXIVAS-Low


Episode 121


What do you do when observational data and RCTs conflict? This week I'm covering the "real world PEXIVAS" study that was done by the French Vasculitis Study Group. Great read, interesting issues, hav…


Published on 6 months ago

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E119: Teclistamab for Rheumatology Writ Large


Episode 120


One of my rare case-report podcasts, a topic that I typically avoid. The craze about CAR-T has also made me a little crazy, though, so I wanted to share what I think may be the ultimate destination f…


Published on 6 months, 4 weeks ago

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E118: The emerging risk of overdiagnosis in RA and PMR


Episode 119


Podcast this week about overdiagnosis! Currently one of my favorite topics and something that I think will be an emerging issue in our field. We recently published a Viewpoint in Lancet Rheumatology …


Published on 7 months, 1 week ago

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E117: Inebilizumab for IgG4-RD (MITIGATE)


Episode 118


New RCT in a new disease with a new drug! But is it as shiny as one would hope? Interesting discussion today about what a trial means, how it will affect practice, and how we could do better as a fie…


Published on 9 months ago





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